Overview
Adult-onset Still's disease (AOSD) is a rare type of inflammatory arthritis that typically affects adults between the ages of 20 and 40. Symptoms include fever, joint pain and swelling, a characteristic salmon-colored rash, and an enlarged spleen and lymph nodes. The cause of AOSD is not well understood, but it is thought to be an autoimmune disorder. Treatment typically involves the use of nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and disease-modifying antirheumatic drugs (DMARDs) to reduce inflammation and control symptoms. In severe cases, immunosuppressant drugs may also be used.