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Last updated date: 15-Feb-2023

Originally Written in English

Amenorrhea: Types, causes, and treatment

    Overview

    Amenorrhea is the absence of menstrual periods in women of reproductive age. There are two types of amenorrhea: primary and secondary. Amenorrhea can be caused by a variety of factors, including pregnancy, menopause, hormonal imbalances, and certain medical conditions such as thyroid disorders, polycystic ovary syndrome (PCOS), and eating disorders. Treatment for amenorrhea depends on the underlying cause and may include hormone therapy, surgery, or lifestyle changes.

     

    How does the Menstrual cycle work?

    Menstrual cycle work

    The menstrual cycle is the monthly process that occurs in the female reproductive system. The cycle is controlled by hormones and is necessary for the production of eggs and the preparation of the uterus for pregnancy. The average menstrual cycle is 28 days long, but it can vary from 21 to 35 days.

    The cycle can be divided into three phases: the menstrual phase, the follicular phase, and the luteal phase.

    -The menstrual phase occurs on the first day of the cycle and lasts for about 5 days. This is when the lining of the uterus is shed, and blood and other materials are expelled from the body through the vagina.

    • The follicular phase begins after the menstrual phase and lasts for about 14 days. During this time, the ovaries are preparing to release an egg. This phase is characterized by the rise in estrogen levels.
    • The luteal phase is the final phase of the menstrual cycle and lasts for about 14 days. During this time, the ovary releases a mature egg, which travels down the fallopian tube. If the egg is fertilized, it will implant in the uterus and pregnancy will occur. If the egg is not fertilized, the lining of the uterus will be shed and the cycle will begin again.

    The menstrual cycle is regulated by the hypothalamus and pituitary gland in the brain, which secrete hormones that control the ovaries. The ovaries then produce estrogen and progesterone, which regulate the menstrual cycle.

     

    What is Amenorrhea? 

    Amenorrhea

    Amenorrhea is the absence of menstrual periods in a woman of reproductive age. It can be classified as primary or secondary. Primary amenorrhea is the absence of menstrual periods by age 16 and secondary amenorrhea is the absence of menstrual periods for three or more consecutive cycles in a woman who has previously had menstrual periods. Amenorrhea can be caused by a variety of factors including pregnancy, menopause, certain medical conditions, and medications.

     

    What causes Amenorrhea?

    Causes Amenorrhea

    Amenorrhea can be caused by a variety of factors, including:

    • Pregnancy: The most common cause of amenorrhea is pregnancy.
    • Menopause: As women approach menopause, the levels of estrogen and progesterone in the body decrease, which can cause menstrual periods to stop.
    • Polycystic ovary syndrome (PCOS): PCOS is a hormonal disorder that can cause irregular or absent periods.
    • Thyroid disorders: An overactive or underactive thyroid gland can disrupt the hormonal balance in the body and cause amenorrhea.
    • Excessive weight loss or gain: Significant weight loss or weight gain can disrupt the hormonal balance in the body and cause amenorrhea.
    • Stress: Stress can cause the body to produce less estrogen and progesterone, which can disrupt the menstrual cycle and cause amenorrhea.
    • Certain medications, such as birth control pills, can also cause amenorrhea.
    • Genetic disorders, such as Turner Syndrome, can also lead to amenorrhea.
    • Certain medical conditions, such as pituitary tumors, can also cause amenorrhea.

    It's important to note that some women may experience temporary amenorrhea due to lifestyle changes, such as significant weight loss or weight gain, or stress, but these causes are usually reversible with proper treatment.

     

    Who is at Risk for Amenorrhea?

    Risk for Amenorrhea
     

    There are several factors that can increase a woman's risk of developing amenorrhea, including:

    • Age: As women approach menopause, their risk of developing amenorrhea increases.
    • Family history: If a woman's mother or sisters have experienced amenorrhea, she may be at an increased risk.
    • Certain medical conditions: Women with conditions such as polycystic ovary syndrome (PCOS), thyroid disorders, or pituitary tumors may be at an increased risk of developing amenorrhea.
    • Lifestyle factors: Women who have a low body weight, participate in heavy exercise, or experience significant stress may be at an increased risk of developing amenorrhea.
    • Medications: Certain medications, such as birth control pills, can also increase a woman's risk of developing amenorrhea.
    • Genetic disorders: Women who have genetic disorders such as Turner Syndrome may also be at an increased risk of developing amenorrhea.

     

    What are the types of Amenorrhea?

    Types of Amenorrhea

    There are two types of amenorrhea: primary and secondary. Primary amenorrhea is when a woman has not started menstruating by the age of 16. Secondary amenorrhea is when a woman who previously had regular menstrual cycles stops menstruating for three or more months. Both types of amenorrhea can be caused by a variety of factors, including hormonal imbalances, pregnancy, stress, weight changes, and certain medications.

     

    Primary Amenorrhea

    Primary amenorrhea is a condition in which a girl has not started menstruating by the age of 16. This can be caused by a variety of factors, including hormonal imbalances, structural abnormalities of the reproductive system, and certain genetic conditions. Some common causes of primary amenorrhea include Turner syndrome, a chromosomal condition that affects development; congenital adrenal hyperplasia, a condition that affects the adrenal glands; and premature ovarian failure, which occurs when the ovaries stop working before the age of 40. Primary amenorrhea can also be caused by lifestyle factors, such as excessive exercise, low body weight, and eating disorders.

     

    Secondary Amenorrhea

    Secondary amenorrhea can have a variety of causes, including pregnancy, menopause, hormonal imbalances, stress, excessive exercise, weight changes, and certain medications. Some common causes of secondary amenorrhea include polycystic ovary syndrome (PCOS), a hormonal disorder that affects the ovaries; thyroid disorders, which can affect the levels of hormones produced by the thyroid gland; and pituitary tumors, which can affect the production of hormones that regulate the menstrual cycle. Other causes of secondary amenorrhea can include a structural problem in the reproductive system, such as uterine fibroids or endometriosis, and certain genetic conditions.

     

    What are the symptoms of Amenorrhea?

    Symptoms of Amenorrhea

    The main symptom of amenorrhea is the absence of menstrual periods. Depending on the underlying cause, there may be other symptoms as well.

    In primary amenorrhea, a woman may also have other symptoms such as breast development, pubic hair growth and body odor, these are due to the onset of puberty.

    In secondary amenorrhea, a woman may experience symptoms such as hot flashes, night sweats, and vaginal dryness, which can be indicative of menopause. In addition, some women with secondary amenorrhea may have symptoms such as acne, excessive hair growth, or weight gain, which can be caused by hormonal imbalances.

    Other possible symptoms of amenorrhea include headaches, fatigue, and changes in mood or sleep patterns. If you have amenorrhea and are experiencing any of these symptoms, it's important to see a healthcare provider for an evaluation.

     

    How is Amenorrhea diagnosed?

    Amenorrhea diagnosed

    Amenorrhea is typically diagnosed based on a woman's menstrual history and a physical examination. A healthcare provider will take a detailed medical history, including information about menstrual patterns, pregnancy, and any symptoms that the woman may be experiencing. The provider will also perform a physical examination, which may include a pelvic examination to check for any structural abnormalities of the reproductive system.

    In order to determine the cause of amenorrhea, a healthcare provider may also order certain diagnostic tests. These may include:

    • Blood tests: To check hormone levels, such as estrogen, progesterone, and follicle-stimulating hormone (FSH).
    • Imaging tests: Such as pelvic ultrasound to examine the uterus, ovaries, and fallopian tubes, or a magnetic resonance imaging (MRI) scan to evaluate the pituitary gland or other structures in the brain.
    • Genetic testing: To check for chromosomal disorders such as Turner's syndrome

    Once the cause of amenorrhea has been determined, a healthcare provider can develop a treatment plan. Treatment for amenorrhea will vary depending on the underlying cause, but may include hormone therapy, surgery, or lifestyle changes.

     

    How is Amenorrhea Treated?

    Amenorrhea Treated

    Amenorrhea, or the absence of menstrual periods, can have many causes and is treated differently depending on the underlying cause. Possible treatments include hormonal therapy, such as birth control pills or hormone replacement therapy, addressing any underlying medical conditions, and weight loss or gain if the individual is underweight or overweight. In some cases, surgery may be necessary. It is important to consult a healthcare provider to determine the best course of treatment for an individual's specific case.

    • Amenorrhea Home Care

    Home care for amenorrhea depends on the underlying cause of the condition. However, some general steps that may be helpful include:

    • Maintaining a healthy weight: If amenorrhea is caused by being underweight or overweight, it may be helpful to try to reach a healthy weight through a balanced diet and regular exercise.
    • Managing stress: Stress can disrupt the hormonal balance in the body and contribute to amenorrhea, so finding ways to manage stress such as yoga, meditation, or therapy may be beneficial.
    • Avoiding smoking and excessive alcohol consumption: These habits can also disrupt the hormonal balance in the body and contribute to amenorrhea.
    • Getting enough rest and maintaining good sleep hygiene: Adequate sleep is important for overall health and can help regulate hormones.

     

    Will I need surgery for Amenorrhea?

    Whether or not surgery is necessary for the treatment of amenorrhea depends on the underlying cause of the condition. In some cases, surgery may be required to address certain structural or anatomical issues that are causing the amenorrhea. For example, surgery may be necessary if amenorrhea is caused by a tumor, a congenital malformation, or a surgical removal of the ovaries or uterus.

    However, in many cases, amenorrhea is caused by hormonal imbalances or other medical conditions that can be treated with medications, hormone therapy, or lifestyle changes, and surgery may not be necessary.

    It's important to consult a healthcare professional, such as an obstetrician-gynecologist or endocrinologist, to determine the cause of your amenorrhea and the best course of treatment. They will be able to recommend if surgery is necessary or not.

     

    Are there Complications of Amenorrhea?

    Complications of Amenorrhea

    Amenorrhea, or the absence of menstrual periods, can have a variety of complications, depending on the underlying cause. Some potential complications include:

    • Infertility: Amenorrhea can make it difficult or impossible to conceive a child.
    • Bone density loss: The absence of menstrual periods can lead to a loss of bone density, increasing the risk of osteoporosis.
    • Hormonal imbalances: Amenorrhea can result in imbalances in estrogen and other hormones, which can cause a variety of symptoms.
    • Psychological distress: The absence of menstrual periods can be distressing for some women and can contribute to feelings of anxiety or depression.
    • Loss of reproductive function: In some cases, amenorrhea may lead to permanent loss of reproductive function.

     

    How Can I Prevent Amenorrhea?

    Prevent Amenorrhea

    Amenorrhea can have a variety of causes, so the best way to prevent it will depend on the underlying cause. However, some general measures that may help reduce the risk of amenorrhea include:

    • Maintaining a healthy weight: Being underweight or overweight can disrupt the balance of hormones that regulate the menstrual cycle, leading to amenorrhea.
    • Eating a balanced diet: Consuming a diet that is rich in fruits, vegetables, whole grains, and lean protein can help support a healthy menstrual cycle.
    • Avoiding excessive exercise: While regular exercise is generally beneficial, excessive physical activity or overexercising can disrupt the menstrual cycle and lead to amenorrhea.
    • Managing stress: Stress can disrupt the balance of hormones that regulate the menstrual cycle, so it's important to find healthy ways to manage stress such as meditation, Yoga, or talking to a therapist.
    • Following a healthy lifestyle: Avoiding smoking and limiting alcohol consumption can help reduce the risk of amenorrhea.

     

    What are the outcomes for people with Amenorrhea?

    Amenorrhea, or the absence of menstrual periods, can have a variety of potential outcomes depending on the underlying cause. Some possible outcomes include:

    • Infertility: If amenorrhea is caused by hormonal imbalances or structural issues in the reproductive system, it can make it difficult or impossible to conceive.
    • Bone loss: The absence of menstrual periods can also lead to decreased levels of estrogen, which can increase the risk of osteoporosis (bone loss) and fractures.
    • Psychological impact: Amenorrhea can also have a psychological impact on those who experience it, particularly if it is related to a condition such as an eating disorder or extreme weight loss.

    It is important to consult a healthcare professional to determine the underlying cause of amenorrhea and to develop an appropriate treatment plan.

     

    When should I see my healthcare provider about Amenorrhea?

    You should see a healthcare provider if you have been experiencing amenorrhea (absence of menstrual periods) and have not yet reached menopause. Additionally, you should see a healthcare provider if you have any of the following symptoms:

    • Vaginal bleeding or spotting that is not related to your menstrual period.
    • Pelvic pain or pressure.
    • Hirsutism (excess hair growth) or acne.
    • Rapid weight gain or weight loss.
    • Headaches or vision changes.
    • Fatigue or weakness.
    • Hot flashes or night sweats.

    If you are experiencing amenorrhea and have a history of eating disorder or other condition that could affect your menstrual cycle, it is especially important to see a healthcare provider.

     

    Living with Amenorrhea

    Living with amenorrhea can have physical and emotional effects on a person, and it is important to speak with a healthcare provider to determine the cause and appropriate treatment. Depending on the cause, treatment options may include hormone replacement therapy, lifestyle changes, or surgery. It's also important to maintain a healthy lifestyle and manage stress to support overall health.

     

    Conclusion 

    Amenorrhea is the absence of menstrual periods. It can be caused by a variety of factors, including pregnancy, menopause, hormonal imbalances, and certain medical conditions. Treatment for amenorrhea depends on the underlying cause and may include hormone therapy, surgery, or lifestyle changes. It is important to consult with a healthcare provider for an accurate diagnosis and appropriate treatment plan.