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Last updated date: 07-Jan-2025

Originally Written in English

Anemia of Chronic Disease: Causes, Symptoms, and Effective Treatments

    Introduction

    Anemia of Chronic Disease (ACD) is a type of anemia that occurs due to chronic infections, inflammatory conditions, or ongoing diseases such as cancer, kidney disease, or autoimmune disorders. Unlike other forms of anemia that are typically caused by nutritional deficiencies or blood loss, ACD is associated with the body’s response to long-term illness. This type of anemia can cause a reduction in the number of red blood cells or hemoglobin in the blood, leading to fatigue, weakness, and other symptoms that can significantly affect a patient’s quality of life.

    In Korea, the management and treatment of ACD have seen substantial advancements. The country's healthcare system incorporates both modern medicine and traditional approaches, making it an attractive option for patients seeking effective treatment. Anemia, particularly in the context of chronic disease, is an important issue that requires timely and precise medical intervention.

    This article delves into the causes, symptoms, and effective treatments of ACD, with a particular focus on the approaches taken in Korea. By understanding the underlying mechanisms of ACD and exploring the latest treatment methods, patients and caregivers can make informed decisions about managing this condition.

    What is Anemia of Chronic Disease?

    Anemia of Chronic Disease is a form of anemia that develops in response to chronic infections, inflammatory diseases, or ongoing conditions like cancer or kidney failure. Unlike typical anemia caused by iron deficiency or blood loss, ACD is a complex condition that involves the body’s immune response. It is often observed in individuals who suffer from long-term, low-grade inflammation. The inflammation can disrupt the body's ability to produce red blood cells efficiently and can alter iron metabolism, preventing it from being used properly.

    Anemia

    The key difference between ACD and other types of anemia is that in ACD, the body still produces normal or even elevated amounts of iron, but the iron is not effectively utilized in the production of red blood cells. Instead, it is sequestered in storage sites such as the liver and spleen, making it unavailable for red blood cell production.

    Chronic conditions that commonly lead to ACD include: