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Last updated date: 04-Apr-2023

Originally Written in English

Intrauterine Growth Restriction

    Overview

    Intrauterine growth restriction (IUGR) is a condition in which a fetus does not grow at the expected rate during pregnancy. This can be due to a variety of factors, including genetic conditions, maternal health conditions, placental problems, and environmental factors. Fetal growth restriction can lead to a variety of complications, including low birth weight, preterm labor, and stillbirth.

    Early diagnosis and proper management of IUGR can help reduce the risk of complications and improve outcomes for both the mother and baby. It is important to speak with a healthcare provider if you have any concerns about fetal growth or development during pregnancy.

     

    What is Intrauterine growth restriction?

    Intrauterine growth restriction

    Intrauterine growth restriction (IUGR) is a condition in which a developing fetus does not grow to its expected size during pregnancy. This can occur due to a variety of factors, including problems with the placenta, maternal health issues, fetal genetic abnormalities, or other environmental factors.

    IUGR is typically diagnosed through ultrasound measurements that show that the fetus is not growing at the expected rate. This condition can increase the risk of certain complications during pregnancy and delivery, including preterm delivery, low birth weight, and fetal distress.

     

    Types of Intrauterine growth restriction

    There are two main types of intrauterine growth restriction (IUGR):

    1. Symmetrical IUGR: In this type, the fetus is small all over, with all body parts being proportionally reduced in size. This is usually caused by genetic factors or maternal health problems that affect fetal growth early in pregnancy.
    2. Asymmetrical (or disproportionate) IUGR: In this type, the fetus has a normal head circumference, but the body is smaller than expected for the gestational age. This is typically caused by problems with the placenta, which can restrict the flow of nutrients and oxygen to the developing fetus. Asymmetrical IUGR is more common and is usually diagnosed later in pregnancy.

    Both types of IUGR can increase the risk of complications during pregnancy and delivery, including preterm birth, low birth weight, and stillbirth. Close monitoring and early intervention may be necessary to reduce these risks and ensure the best possible outcome for both the mother and baby.

     

    What causes Restricted fetal growth?

    Restricted fetal growth or intrauterine growth restriction (IUGR) can be caused by a variety of factors, including:

    1. Problems with the placenta: The placenta plays a crucial role in delivering nutrients and oxygen to the developing fetus. If the placenta is damaged or not functioning properly, this can lead to restricted fetal growth.
    2. Maternal health issues: Maternal health problems such as high blood pressure, diabetes, kidney disease, and infections can affect fetal growth by restricting blood flow to the placenta and reducing the availability of nutrients and oxygen to the fetus.
    3. Fetal genetic abnormalities: Some genetic abnormalities can affect fetal growth, leading to IUGR.
    4. Environmental factors: Exposure to harmful substances such as tobacco and alcohol during pregnancy can affect fetal growth.
    5. Multiple pregnancy: Twins, triplets, or other multiple pregnancies may be at increased risk of IUGR due to limited space and resources in the uterus.

    It is important for pregnant women to receive proper prenatal care and to inform their healthcare providers of any medical conditions or concerns that may affect fetal growth. Regular ultrasounds and fetal monitoring can help identify IUGR early and ensure timely intervention to reduce the risks associated with this condition.

     

    What are the symptoms of Intrauterine growth restriction?

    Symptoms of Intrauterine growth restriction

    Intrauterine growth restriction (IUGR) may not cause any noticeable symptoms in the mother, and it may only be detected through ultrasound measurements that show that the fetus is not growing at the expected rate. However, in some cases, there may be signs or symptoms that warrant further evaluation, including:

    1. Decreased fetal movement: A decrease in the number of fetal movements can be an early sign of fetal distress.
    2. Fundal height measurement: The measurement of the distance from the pubic bone to the top of the uterus (fundal height) may be smaller than expected for the gestational age.
    3. Low amniotic fluid levels: IUGR may be associated with decreased amniotic fluid levels, which can be detected by ultrasound.
    4. Abnormal fetal heart rate: IUGR may be associated with an abnormal fetal heart rate, which may indicate fetal distress.

    If IUGR is suspected, further evaluation and monitoring may be necessary to assess fetal well-being and determine the best course of management. Pregnant women who have concerns about fetal growth or any other pregnancy-related symptoms should contact their healthcare provider for evaluation and management.

     

    How is Intrauterine growth restriction diagnosed?

    Intrauterine growth restriction diagnosed

    Intrauterine growth restriction (IUGR) is typically diagnosed through a combination of ultrasound measurements and clinical evaluation. Here are some common methods used to diagnose IUGR:

    1. Ultrasound: Regular ultrasounds are typically used to monitor fetal growth throughout pregnancy. If a fetus is measuring smaller than expected for gestational age, this may be a sign of IUGR.
    2. Doppler ultrasound: This test uses sound waves to measure blood flow in the umbilical artery, which can be an indicator of placental function. Abnormal blood flow patterns may be a sign of IUGR.
    3. Biophysical profile (BPP): This test combines an ultrasound evaluation of fetal breathing, movement, tone, and amniotic fluid volume, along with a non-stress test (NST) to assess fetal well-being.
    4. Maternal serum screening: This blood test can assess the risk of chromosomal abnormalities and other fetal conditions that may affect growth.
    5. Fundal height measurement: This is a measurement of the distance from the pubic bone to the top of the uterus (fundal height) which may be smaller than expected for the gestational age in cases of IUGR.

    If IUGR is suspected, the healthcare provider may recommend additional testing and monitoring to assess fetal well-being and determine the best course of management. Early detection and intervention are crucial to reducing the risks associated with IUGR and ensuring the best possible outcome for both the mother and baby.

     

    Treatments options for fetal growth restriction

    Treatments options for fetal growth restriction

    The treatment options for intrauterine growth restriction (IUGR) depend on the underlying cause, the severity of the condition, and the gestational age of the fetus. Here are some possible treatment options:

    1. Increased monitoring: If IUGR is detected, the healthcare provider may recommend more frequent ultrasounds and other monitoring tests to assess fetal well-being.
    2. Nutritional support: Adequate nutrition is important for fetal growth, so the healthcare provider may recommend a balanced diet and may also suggest nutritional supplements, such as iron or folic acid.
    3. Medications: In some cases, medications may be used to improve blood flow to the placenta or to treat underlying medical conditions that may be contributing to IUGR.
    4. Bed rest: In cases of severe IUGR or fetal distress, the healthcare provider may recommend bed rest or hospitalization to monitor the fetus more closely.
    5. Early delivery: If the fetus is not growing at a rate that is sufficient for its gestational age and/or there are signs of fetal distress, the healthcare provider may recommend early delivery. In some cases, this may involve inducing labor, while in other cases, a cesarean delivery may be necessary.

     

    How is Intrauterine growth restriction (IUGR) treated after birth?

    Treatment for intrauterine growth restriction (IUGR) after birth will depend on the severity of the condition and the specific needs of the baby. In general, the baby will be closely monitored for signs of complications and provided with any necessary medical support.

    Some possible treatments for IUGR after birth may include:

    1. Feeding support: IUGR babies may have difficulty feeding due to their small size and may need extra help with breastfeeding or bottle-feeding. In some cases, they may require tube feeding or intravenous nutrition.
    2. Temperature support: IUGR babies may have difficulty regulating their body temperature, and may require extra warmth from an incubator or other medical equipment.
    3. Oxygen therapy: If the baby is having difficulty breathing or maintaining healthy oxygen levels, they may require supplemental oxygen therapy.
    4. Medications: In some cases, medications may be needed to treat specific complications related to IUGR, such as high blood pressure or anemia.
    5. Surgery: Rarely, IUGR may cause complications that require surgical intervention.

     

    What are possible complications of FGR?

    Complications of FGR

    Intrauterine growth restriction (IUGR) can lead to a number of potential complications for both the mother and the fetus. Here are some of the possible complications associated with FGR:

    1. Preterm birth: FGR can increase the risk of preterm labor and delivery, which can increase the risk of complications for the fetus.
    2. Low birth weight: Babies with FGR are often born with a low birth weight, which can increase the risk of health problems in the newborn period, such as breathing difficulties and feeding problems.
    3. Neonatal morbidity: Babies with FGR are at increased risk of a range of complications in the neonatal period, including hypoglycemia, hypothermia, and neonatal sepsis.
    4. Stillbirth: Severe IUGR can increase the risk of stillbirth.
    5. Placental abnormalities: FGR can be caused by problems with the placenta, which can lead to a range of complications, such as placental insufficiency or placental abruption.
    6. Long-term developmental problems: FGR has been associated with an increased risk of long-term developmental problems, such as cognitive deficits and behavioral problems.
    7. Maternal complications: In severe cases, FGR can lead to complications for the mother, such as preeclampsia, gestational diabetes, and placental abnormalities.

     

    How can I prevent Intrauterine growth restriction?

    Preventing intrauterine growth restriction (IUGR) may not always be possible, as some cases are caused by genetic or medical factors beyond a mother's control. However, there are some steps a mother can take to reduce the risk of IUGR:

    1. Prenatal care: Regular prenatal care is important for monitoring fetal growth and identifying any potential problems early on. Attend all scheduled prenatal appointments and follow your healthcare provider's recommendations.
    2. Healthy lifestyle: A healthy lifestyle, including regular exercise and a balanced diet, can help promote optimal fetal growth. Avoid alcohol, tobacco, and illicit drugs during pregnancy.
    3. Manage medical conditions: Manage any chronic medical conditions, such as diabetes, high blood pressure, or kidney disease, to reduce the risk of IUGR.
    4. Manage infections: Infections during pregnancy can increase the risk of IUGR. Follow good hygiene practices and seek prompt treatment for any infections.
    5. Avoid environmental toxins: Exposure to certain environmental toxins, such as lead or mercury, can increase the risk of IUGR. Take precautions to avoid exposure to these toxins.

     

    Does fetal growth Restriction cause early labor?

    In some cases, fetal growth restriction (FGR) can lead to early labor and delivery. This is because when a fetus is not growing properly, the placenta may not be functioning as it should, which can cause the release of hormones that can trigger labor. Additionally, when a fetus is not getting enough oxygen and nutrients, it may become stressed, which can also trigger labor.

    However, it's important to note that not all cases of FGR will result in early labor. The risk of preterm labor and delivery will depend on a variety of factors, including the severity of the FGR, the presence of any other complications, and the gestational age of the fetus.

    If you are concerned about fetal growth or preterm labor, it's important to speak with your healthcare provider. Regular prenatal care and monitoring can help identify any potential problems early on and reduce the risk of complications.

     

    Conclusion 

    In conclusion, fetal growth restriction (FGR) is a condition in which a fetus does not grow at the expected rate during pregnancy. FGR can be caused by a variety of factors, including genetic conditions, maternal health conditions, placental problems, and environmental factors. The condition can lead to a variety of complications, including preterm labor, low birth weight, and stillbirth.

    Diagnosis of FGR typically involves regular ultrasound monitoring of fetal growth and development. Treatment options may include close monitoring, early delivery, or other medical interventions to support fetal growth and development.

    While it may not always be possible to prevent FGR, there are steps that pregnant women can take to reduce their risk, including attending regular prenatal care appointments, adopting a healthy lifestyle, managing chronic medical conditions, avoiding environmental toxins, and seeking prompt treatment for infections. If you have any concerns about fetal growth or development during pregnancy, be sure to speak with your healthcare provider.