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Last updated date: 13-Feb-2023

Originally Written in English

Stem cell-based regenerative medicine

  • CloudHospital

  • General Health

  • Stem cell-based regenerative medicine

Overview

Many people wonder what stem cells are as the topic is often mentioned lately. Stem cells are one of the main cells of the human body that have the ability to grow more than two hundred types of body cells. Stem cells are non-specialized cells that can be transformed into highly specialized cells in the body. In the other words, Stem cells are undifferentiated cells with self-renewal potential, differentiation into several types of cells and excessive proliferation. 

In the past, it was believed that stem cells can only differentiate into mature cells of the same organ. Today, there is much evidence to show that stem cells can differentiate into the other types of cells including ectoderm, mesoderm, and endoderm. The quantity of stem cells is different depending the source tissues such as bone marrow, liver, heart, kidney, and others. Over the past two decades much attention has been paid to stem cell research. Therefore, there is now a great increase in the understanding of its characteristics and the therapeutic applications potential. Today, the utilization of these cells in experimental research and cell therapy represents in such disorders including hematological, skin regeneration and heart disease. Due to the power of being able to utilize stem cells to regenerate damaged or lacking cells in the body, regenerative medicine reliant on stem cell technology has been a key component of advanced treatments by researchers and hospitals that are able to accommodate such endeavors.

More specifically, regenerative medicine is the emerging branch of medical science that deals with functional restoration of tissues or organs for the patient suffering from severe injuries or chronic diseases. The spectacular progress in the field of stem cell research has laid the foundation for stem cell-based therapies of disease which cannot be cured by conventional methods. The ample self-renewal and potential to differentiate into other types of needed bodily cells translates to stem cells clearly being the next frontier of regenerative medicine. The transdifferentiating potential of stem cells varies with source and according to that regenerative applications also change. Advancements in gene editing and tissue engineering technology have endorsed the ex vivo remodeling of stem cells grown into organoids and tissue structures for personalized applications. In other words, organs may become tailor made outside the body and implanted when completed similar to automobile parts being installed in older cars to prolong their lives. The applications are seemingly endless including spinal cord injuries, cardiovascular diseases, liver injuries, glaucoma, diabetes, osteoarthritis, dentistry (growing teeth), corneal diseases, muscular deformities, bladder deformities, bone degeneration, alopecia, anemia and blood cancer, lung degeneration, etc. The possibilities are seemingly endless. In this arena, Korea has been at the forefront and there are excellent hospitals that are pioneering in the field of stem cell research as well as applications and practice. One formidable hospital is Samsung Medical Center’s Stem Cell & Regenerative Medicine Institute in Seoul, South Korea.

The Stem Cell & Regenerative Medicine institute was launched to develop novel medical technologies to restore impaired tissues or organs damaged due to aging, diseases, or accidents. The institute has mainly focused on translational researches and the development of novel medical therapeutics for incurable and refractory diseases utilizing stem cells.

The main target diseases and research fields are musculoskeletal and joint diseases, stroke, dementia and degenerative brain disease, incurable diseases of preterm infants, hematopoietic stem cell transplantation, peripheral nerve disorders, hepatocyte regeneration, blood vessel disease, intractable diabetes, kidney disease, spinal cord damage, brain tumor, transplantation immunity, and hair loss and skin regeneration.

Samsung Medical Center is a key partner with CloudHospital and has been with us from our inception. For those looking for a seamless “start to finish” process of handling all the details for patients, CloudHospital is the best choice.