Acute Lymphocytic Leukemia (ALL)

Acute Lymphocytic Leukemia (ALL) is a B or T lymphoblastic neoplasm characterized by abnormal development of aberrant, immature cells and their precursors, which eventually results in the replacement of bone marrow and other lymphoid tissues, resulting in the classic Acute Lymphocytic Leukemia clinical pattern. In the United States, Acute Lymphocytic Leukemia represents about 2 percent of all lymphoid malignancies identified. Males are somewhat more likely than females to have Acute Lymphocytic Leukemia, and Whites are three times more likely than Blacks to develop the disease. Because the tumor has replaced the bone marrow, patients with Acute Lymphocytic Leukemia usually have symptoms like anemia, thrombocytopenia, and neutropenia. Tiredness, frequent or spontaneous bruising/bleeding, and infections are all possible symptoms. Fever, nocturnal sweats, and unintended weight loss are common B-symptoms, but they might be minor. On presentation, liver enlargement, spleen enlargement, and lymphadenopathy can be detected in approximately half of the individuals. Central nervous system involvement is common, and it might be associated with cranial neuropathies or symptoms, mostly meningeal, that are connected to increased intracranial pressure.

What is Acute Lymphocytic Leukemia ALL?

Acute lymphocytic leukemia is one of the different types of acute leukemia. Acute lymphoblastic leukemia is another name for it. If it isn't treated, acute implies that it will typically develop worse soon. The most frequent type of cancer in children is acute lymphocytic leukemia. Adults can be affected as well.