Hodgkin’s lymphoma
Hodgkin lymphoma accounts for around one-third of all lymphomas. The absolute incidence has remained constant throughout the years. Hodgkin lymphoma begins in lymph nodes, most commonly in the cervical area, and spreads to neighboring lymph nodes. The majority of those afflicted are young adults. Hodgkin lymphoma has a pediatric variant that is more common in developing countries. Hodgkin lymphoma has a male predominance, although this male predominance is not evident in the nodular sclerosis subtype.
Tumor cells are frequently found in relatively small numbers in neoplastic tissues. A low number of scattered tumor cells reside in an enormous heterogeneous admixture of nonneoplastic inflammatory and supportive cells. Background cells, lymphocytes, histiocytes, plasma cells, eosinophils, and neutrophils are all present due to the production and release of cytokines by tumor cells.