Non-Hodgkin's lymphoma

Non-Hodgkin lymphomas are a heterogeneous group of malignancies of the lymphoid system. Non-Hodgkin lymphoma is divided into subgroups, each having its own epidemiology, etiology, immunophenotypic, genetic, clinical characteristics, and response to therapy. Based on the disease's prognosis, it is classified as 'indolent' or 'aggressive.

These diseases have been categorized as B-cell and T-cell neoplasms by the World Health Organization's classification of hematological and lymphoid malignancies. B-cell lymphomas account for roughly 90% of all lymphomas, with follicular lymphoma and diffuse large B-cell lymphoma being the two most frequent histological disease types. 

Approximately 55,000 to 60,000 new cases of non-Hodgkin lymphoma are diagnosed annually in the United States, a number that has nearly doubled during the past 3 decades.