Transurethral Incision of The Prostate (TUIP)

The surgical method of transurethral incision of the prostate (TUIP) was established in the mid-nineteenth century. The first descriptions originate from 1834 when Guthrie proposed that the bladder neck be mechanically dilacerated. There are no clinical statistics on the number of interventions or Guthrie's outcomes, however. During the same time period, Bottini presented a diathermy-based approach. However, TUIP was not widely seen as a feasible alternative for the management of prostate adenoma at the time.

Keitzer first introduced the TUIP procedure as an endoscopic option for addressing sub-vesical blockage in younger patients with tiny prostate adenomas. The technique differs from transurethral resection of the prostate (TURP) in that it removes the obstruction by reducing the constrictive tonus following prostatic incision (and not by tissue removal, as in the case of TURP).

Since its introduction, TUIP has steadily gained traction in the therapeutic arsenal, owing to its ease of use, low risk of complications, and long-term effectiveness. Furthermore, most authors believe that this strategy is simple to master. Orandi presented the first long-term outcomes, recommending TUIP as a possible therapeutic option in young patients with moderate prostate sizes or concomitant diseases that preclude resection. In the absence of severe obstructive symptoms, however, the intervention is not indicated.