Repeated Implantation Failure (RIF)

Overview

Repeated embryo implantation failure (RIF) is a very frustrating disease for both patients and professionals, and treating it is one of the most challenging issues in the area of in vitro fertilization (IVF). Uterine anatomic abnormalities, thrombophilia, non-receptive endometrium, and immunological variables are examples of maternal factors. 

Failure to implant owing to embryonic reasons is related with either genetic defects or other embryonic factors that impede the embryo's capacity to grow in utero, hatch, and implant. New methods of time-lapse imaging of embryos and assessing their metabolic activities may enhance embryo selection and subsequent results for IVF patients and those diagnosed with RIF.